Bernd Giebel

berndBernd Giebel studied biology at the University zu Köln and received his PhD in 1996 at the Institute for Developmental Biology in Köln: In his thesis he investigated aspects of the Notch signaling pathway during early neurogenesis of Drosophila melanogaster. In 1999 he moved to the Heinrich-Heine-University of Düsseldorf and started to work with human hematopoietic stem and progenitor cells. There, he also established his research group focusing on mechanisms, which control the decision of self-renewal versus differentiation of human somatic stem cells. In 2008 he received the venia legendi for Molecular Medicine. In November of the same year he moved with his group to the Institute of Transfusion Medicine at the University Hopital Essen. Here, he continues his studies on human somatic stem cells. Via the identification of two asymmetrically segregating proteins in dividing human hematopoietic stem and progenitor cells, the tetraspanins CD53 and CD63, he became interested in exososomes, small extracellular vesicles (EVs) participating in intercellular communication. Currently, as a second topic, his group establishes techniques to purify and analyze mesenchymal stem cell (MSC)-derived EVs for clinical applications

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